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    AIM17 Aim17p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856365, updated on 9-Dec-2024

    Summary

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    Official Symbol
    AIM17
    Official Full Name
    Aim17p
    Primary source
    SGD:S000001013
    Locus tag
    YHL021C
    See related
    AllianceGenome:SGD:S000001013; FungiDB:YHL021C; VEuPathDB:YHL021C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    FMP12
    Summary
    Predicted to enable dioxygenase activity and metal ion binding activity. Involved in mitochondrion organization. Located in mitochondrion. Orthologous to human BBOX1 (gamma-butyrobetaine hydroxylase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See AIM17 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (64462..65859, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene tRNA-His Neighboring gene DNA topoisomerase (ATP-hydrolyzing) Neighboring gene transcriptional regulator OPI1 Neighboring gene Apm2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Putative mitochondrial α-ketoglutarate-dependent dioxygenase Fmp12 controls utilization of proline as an energy source in Saccharomyces cerevisiae. Nishida I, et al. Microb Cell, 2016 Sep 19. PMID 28357320, Free PMC Article
    2. Mutations of the TATA-binding protein confer enhanced tolerance to hyperosmotic stress in Saccharomyces cerevisiae. Kim NR, et al. Appl Microbiol Biotechnol, 2013 Sep. PMID 23709042
    3. Construction of Saccharomyces cerevisiae strains with enhanced ethanol tolerance by mutagenesis of the TATA-binding protein gene and identification of novel genes associated with ethanol tolerance. Yang J, et al. Biotechnol Bioeng, 2011 Aug. PMID 21437883
    4. Regulation of lipid droplet dynamics in Saccharomyces cerevisiae depends on the Rab7-like Ypt7p, HOPS complex and V1-ATPase. Bouchez I, et al. Biol Open, 2015 May 6. PMID 25948753, Free PMC Article
    5. A Genetic Screen To Identify Genes Influencing the Secondary Redox Couple NADPH/NADP(+) in the Yeast Saccharomyces cerevisiae. Yadav S, et al. G3 (Bethesda), 2020 Jan 7. PMID 31757928, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carnitine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Aim17p
    NP_011842.1
    • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      64462..65859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179101.1 → NP_011842.1  TPA: Aim17p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011842.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKP4, P23180
      UniProtKB/TrEMBL
      A6ZSN0, C7GIR5, G2WF45, N1P9H9
      Conserved Domains (1) summary
      cd00250
      Location:128 → 448
      CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P23180.2

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