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    SNR52 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164886, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SNR52
    Primary source
    SGD:S000006443
    Locus tag
    YNCE0020C
    See related
    AllianceGenome:SGD:S000006443
    Gene type
    ncRNA
    RNA name
    snoRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rRNA 2'-O-ribose methylation guide activity. Involved in rRNA methylation. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SNR52 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (431129..431220, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Pmd1p Neighboring gene type 1 serine/threonine-protein phosphatase catalytic subunit GLC7 Neighboring gene tRNA-His

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage. Lapeyre B, et al. Mol Cell, 2004 Nov 19. PMID 15546625
    2. Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Bonnerot C, et al. Mol Cell, 2003 Nov. PMID 14636587
    3. Loss of Conserved rRNA Modifications in the Peptidyl Transferase Center Leads to Diminished Protein Synthesis and Cell Growth in Budding Yeast. Leppik M, et al. Int J Mol Sci, 2024 May 10. PMID 38791231, Free PMC Article
    4. Optimization of ribosome structure and function by rRNA base modification. Baxter-Roshek JL, et al. PLoS One, 2007 Jan 24. PMID 17245450, Free PMC Article
    5. Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis. Paul A, et al. RNA, 2019 Apr. PMID 30700579, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of large subunit (LSU) rRNA at position U2921 and small subunit (SSU) rRNA at position A420

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA 2'-O-ribose methylation guide activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables rRNA 2'-O-ribose methylation guide activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables rRNA 2'-O-ribose methylation guide activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in rRNA methylation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in rRNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA methylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of box C/D methylation guide snoRNP complex IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleolus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      431129..431220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132170.1 RNA Sequence

      Status: REVIEWED

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