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    MRPS28 mitochondrial 37S ribosomal protein MRPS28 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851937, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MRPS28
    Official Full Name
    mitochondrial 37S ribosomal protein MRPS28
    Primary source
    SGD:S000002745
    Locus tag
    YDR337W
    See related
    AllianceGenome:SGD:S000002745; FungiDB:YDR337W; VEuPathDB:YDR337W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uS15m
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Orthologous to human MRPS15 (mitochondrial ribosomal protein S15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MRPS28 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1146319..1147179)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene karyopherin MSN5 Neighboring gene Mrx8p Neighboring gene uncharacterized protein Neighboring gene rRNA-processing protein FCF1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural and functional analyses of a yeast mitochondrial ribosomal protein homologous to ribosomal protein S15 of Escherichia coli. Dang H, et al. Nucleic Acids Res, 1990 Dec 11. PMID 2263452, Free PMC Article
    2. Two inactive fragments derived from the yeast mitochondrial ribosomal protein MrpS28 function in trans to support ribosome assembly and respiratory growth. Huff MO, et al. J Mol Biol, 1993 Oct 20. PMID 8411167
    3. Derivatives of the yeast mitochondrial ribosomal protein MrpS28 replace ribosomal protein S15 as functional components of the Escherichia coli ribosome. Li Y, et al. J Mol Biol, 1993 Oct 20. PMID 8411168
    4. Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated. Pogoda E, et al. Biogerontology, 2021 Aug. PMID 34052951, Free PMC Article
    5. Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues. Saveanu C, et al. J Biol Chem, 2001 May 11. PMID 11278769

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 37S ribosomal protein MRPS28
    NP_010624.3
    • Mitochondrial ribosomal protein of the small subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1146319..1147179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180645.3 → NP_010624.3  TPA: mitochondrial 37S ribosomal protein MRPS28 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010624.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSW9, P21771
      UniProtKB/TrEMBL
      A6ZYU0, B3LFW0, B5VGM0, C7GWN4, C8Z5P9, G2WB77, N1P6Z0
      Conserved Domains (1) summary
      pfam00312
      Location:161 → 236
      Ribosomal_S15; Ribosomal protein S15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P21771.1

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