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    NGG1 histone acetyltransferase NGG1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851756, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NGG1
    Official Full Name
    histone acetyltransferase NGG1
    Primary source
    SGD:S000002583
    Locus tag
    YDR176W
    See related
    AllianceGenome:SGD:S000002583; FungiDB:YDR176W; VEuPathDB:YDR176W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ADA3; SWI7
    Summary
    Contributes to histone acetyltransferase activity. Involved in chromatin organization. Part of ADA complex; SAGA complex; and SLIK (SAGA-like) complex. Orthologous to human TADA3 (transcriptional adaptor 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See NGG1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (814452..816560)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Hmo1p Neighboring gene mitochondrial 37S ribosomal protein RSM24 Neighboring gene E2 ubiquitin-conjugating protein UBC1 Neighboring gene succinate dehydrogenase membrane anchor subunit SDH4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors. vom Baur E, et al. Genes Dev, 1998 May 1. PMID 9573045, Free PMC Article
    2. Expression and purification of recombinant yeast Ada2/Ada3/Gcn5 and Piccolo NuA4 histone acetyltransferase complexes. Barrios A, et al. Methods, 2007 Mar. PMID 17309836, Free PMC Article
    3. ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2. Piña B, et al. Mol Cell Biol, 1993 Oct. PMID 8413201, Free PMC Article
    4. Structure/functional properties of the yeast dual regulator protein NGG1 that are required for glucose repression. Brandl CJ, et al. J Biol Chem, 1996 Apr 19. PMID 8621592
    5. ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription. Marcus GA, et al. Mol Cell Biol, 1996 Jun. PMID 8649430, Free PMC Article

    See all (161) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    contributes_to histone acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ADA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SLIK (SAGA-like) complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    histone acetyltransferase NGG1
    NP_010461.3
    • Subunit of chromatin modifying histone acetyltransferase complexes; member of the ADA complex, the SAGA complex, and the SLIK complex; transcriptional regulator involved in glucose repression of Gal4p-regulated genes

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      814452..816560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180483.3 → NP_010461.3  TPA: histone acetyltransferase NGG1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010461.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSF8, P32494
      UniProtKB/TrEMBL
      B3LGA7, C7GN21
      Conserved Domains (1) summary
      pfam10198
      Location:506 → 648
      Ada3; Histone acetyltransferases subunit 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32494.1

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