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    OCA2 Oca2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855668, updated on 9-Dec-2024

    Summary

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    Official Symbol
    OCA2
    Official Full Name
    Oca2p
    Primary source
    SGD:S000005001
    Locus tag
    YNL056W
    See related
    AllianceGenome:SGD:S000005001; FungiDB:YNL056W; VEuPathDB:YNL056W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable inositol diphosphate tetrakisphosphate diphosphatase activity and phosphatase activity. Predicted to be involved in protein dephosphorylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See OCA2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (517249..517842)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Arp5p Neighboring gene uncharacterized protein Neighboring gene porin POR1 Neighboring gene tRNA-Asp

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide. Alic N, et al. Mol Biol Cell, 2001 Jun. PMID 11408586, Free PMC Article
    2. Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Wishart MJ, et al. Trends Biochem Sci, 1998 Aug. PMID 9757831
    3. Lipid hydroperoxides activate the mitogen-activated protein kinase Mpk1p in Saccharomyces cerevisiae. Alic N, et al. J Biol Chem, 2003 Oct 24. PMID 12912987
    4. Cytoplasmic Control of Sense-Antisense mRNA Pairs. Sinturel F, et al. Cell Rep, 2015 Sep 22. PMID 26344770
    5. A complex-based reconstruction of the Saccharomyces cerevisiae interactome. Wang H, et al. Mol Cell Proteomics, 2009 Jun. PMID 19176519, Free PMC Article

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol diphosphate tetrakisphosphate diphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Oca2p
    NP_014342.3
    • hypothetical protein; similar to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      517249..517842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182895.3 → NP_014342.3  TPA: Oca2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014342.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1C2, P53949, Q6B2U7
      UniProtKB/TrEMBL
      A6ZS22, B3LNR7, B5VQY6, C7GLU5, C8ZGH2, G2WM47, N1P4I4
      Conserved Domains (1) summary
      cd17661
      Location:4 → 151
      PFA-DSP_Oca2; atypical dual specificity phosphatases similar to oxidant-induced cell-cycle arrest protein 2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53949.1

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