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    Trmt13 tRNA methyltransferase 13 homolog [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499697, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Trmt13provided by RGD
    Official Full Name
    tRNA methyltransferase 13 homologprovided by RGD
    Primary source
    RGD:1565211
    See related
    EnsemblRapid:ENSRNOG00000015140 AllianceGenome:RGD:1565211
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc76
    Summary
    Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation. Orthologous to human TRMT13 (tRNA methyltransferase 13 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 167.5), Muscle (RPKM 99.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Trmt13 in Genome Data Viewer
    Location:
    2q42
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (207217399..207232467, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (204533630..204547711, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (219615665..219628824, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485678 Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene dihydrolipoamide branched chain transacylase E2 Neighboring gene leucine rich repeat containing 39 Neighboring gene SAS-6 centriolar assembly protein Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene uncharacterized LOC102548510 Neighboring gene solute carrier family 35 member A3 Neighboring gene amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC124992

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA 2'-O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA:m(4)X modification enzyme TRM13 homolog
    Names
    coiled-coil domain containing 76
    tRNA guanosine-2'-O-methyltransferase TRM13 homolog
    NP_001029074.2
    XP_038958872.1
    XP_038958875.1
    XP_038958876.1
    XP_038958877.1
    XP_038958878.1
    XP_038958881.1
    XP_063138476.1
    XP_063138477.1
    XP_063138478.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033902.2 → NP_001029074.2  tRNA:m(4)X modification enzyme TRM13 homolog

      See identical proteins and their annotated locations for NP_001029074.2

      Status: PROVISIONAL

      Source sequence(s)
      BC166503
      UniProtKB/TrEMBL
      A6HVA0, B2GV29, F1MAP3
      Related
      ENSRNOP00000062314.2, ENSRNOT00000064484.5
      Conserved Domains (3) summary
      pfam05206
      Location:165 → 469
      TRM13; Methyltransferase TRM13
      pfam05253
      Location:59 → 80
      zf-U11-48K; U11-48K-like CHHC zinc finger
      pfam11722
      Location:17 → 45
      zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      207217399..207232467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102948.2 → XP_038958876.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

      Conserved Domains (1) summary
      pfam05206
      Location:24 → 328
      TRM13; Methyltransferase TRM13

    2. XM_039102949.2 → XP_038958877.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

      Conserved Domains (1) summary
      pfam05206
      Location:24 → 328
      TRM13; Methyltransferase TRM13

    3. XM_039102953.2 → XP_038958881.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

      Conserved Domains (1) summary
      pfam05206
      Location:24 → 328
      TRM13; Methyltransferase TRM13

    4. XM_039102947.2 → XP_038958875.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

      Conserved Domains (1) summary
      pfam05206
      Location:24 → 328
      TRM13; Methyltransferase TRM13

    5. XM_039102950.2 → XP_038958878.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X3

      Conserved Domains (1) summary
      pfam05206
      Location:24 → 328
      TRM13; Methyltransferase TRM13

    6. XM_039102944.2 → XP_038958872.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X1

      UniProtKB/TrEMBL
      A6HVA0
      Conserved Domains (3) summary
      pfam05206
      Location:165 → 444
      TRM13; Methyltransferase TRM13
      pfam05253
      Location:59 → 80
      zf-U11-48K; U11-48K-like CHHC zinc finger
      pfam11722
      Location:17 → 45
      zf-TRM13_CCCH; CCCH zinc finger in TRM13 protein

    7. XM_063282406.1 → XP_063138476.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X2

      UniProtKB/TrEMBL
      A6HVA0

    8. XM_063282408.1 → XP_063138478.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X5

    9. XM_063282407.1 → XP_063138477.1  tRNA:m(4)X modification enzyme TRM13 homolog isoform X4

    RNA

    1. XR_010063655.1 RNA Sequence

    2. XR_010063656.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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