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    swsn-7 ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component [ Caenorhabditis elegans ]

    Gene ID: 174286, updated on 9-Dec-2024

    Summary

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    Official Symbol
    swsn-7
    Official Full Name
    ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component
    Primary source
    WormBase:WBGene00007433
    Locus tag
    CELE_C08B11.3
    See related
    AllianceGenome:WB:WBGene00007433
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Is expressed in intestine and nervous system. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 6; colorectal cancer; and hepatocellular carcinoma. Orthologous to human ARID2 (AT-rich interaction domain 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See swsn-7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (8022632..8027763, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Early embryogenesis protein zyg-11 Neighboring gene ncRNA Neighboring gene Putative histone deacetylase 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nose resistant to fluoxetine protein 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The conserved PBAF nucleosome-remodeling complex mediates the response to stress in Caenorhabditis elegans. Kuzmanov A, et al. Mol Cell Biol, 2014 Mar. PMID 24421384, Free PMC Article
    2. Comprehensive single cell-resolution analysis of the role of chromatin regulators in early C. elegans embryogenesis. Krüger AV, et al. Dev Biol, 2015 Feb 15. PMID 25446273
    3. SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans. Mathies LD, et al. Proc Natl Acad Sci U S A, 2015 Mar 10. PMID 25713357, Free PMC Article
    4. Gene expression profiling of epidermal cell types in C. elegans using Targeted DamID. Katsanos D, et al. Development, 2021 Sep 1. PMID 34397094, Free PMC Article
    5. A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target. Andachi Y. RNA, 2008 Nov. PMID 18824511, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of SWI/SNF superfamily-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ARID domain-containing protein;SWI/SNF nucleosome remodeling complex component
    NP_001348697.1
    • Confirmed by transcript evidence
    NP_495679.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8022632..8027763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001361864.4 → NP_001348697.1  ARID domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2K5ATP7
      Conserved Domains (2) summary
      smart00501
      Location:25 → 116
      BRIGHT; ARID (A/T-rich interaction domain) domain
      pfam15790
      Location:1088 → 1199
      EP400_N; E1A-binding protein p400, N-terminal

    2. NM_063278.6 → NP_495679.1  SWI/SNF nucleosome remodeling complex component [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495679.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09441
      Conserved Domains (1) summary
      smart00501
      Location:25 → 116
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09441.1

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