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    nhr-13 Nuclear hormone receptor family member nhr-13 [ Caenorhabditis elegans ]

    Gene ID: 178696, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-13
    Official Full Name
    Nuclear hormone receptor family member nhr-13
    Primary source
    WormBase:WBGene00003612
    Locus tag
    CELE_Y5H2B.2
    See related
    AllianceGenome:WB:WBGene00003612
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-13 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (2192485..2196827)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF2250 domain-containing protein Neighboring gene Serpentine Receptor, class BC (Class B-like) Neighboring gene Cytochrome P450 4c3 Neighboring gene CYtochrome P450 family Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans. Zeng L, et al. PLoS Genet, 2021 Jul. PMID 34237064, Free PMC Article
    2. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear hormone receptor family member nhr-13
    NP_001024268.1
    • Confirmed by transcript evidence
    NP_001024269.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2192485..2196827
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029098.6 → NP_001024269.1  Nuclear hormone receptor family member nhr-13 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024269.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6F3C8, Q9N4Q7
      UniProtKB/TrEMBL
      Q9XYB8
      Conserved Domains (2) summary
      cd06157
      Location:198 → 382
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
      smart00399
      Location:21 → 79
      ZnF_C4; c4 zinc finger in nuclear hormone receptors

    2. NM_001029097.6 → NP_001024268.1  Nuclear hormone receptor family member nhr-13 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024268.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XYB8
      Conserved Domains (2) summary
      cd06157
      Location:198 → 384
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
      smart00399
      Location:21 → 79
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4Q7.3

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