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    ztf-23 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 171880, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ztf-23
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00021846
    Locus tag
    CELE_Y54E10BR.8
    See related
    AllianceGenome:WB:WBGene00021846
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ztf-23 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    12
    Sequence:
    Chromosome: I; NC_003279.8 (3052048..3059165, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor-related protein 1 Neighboring gene DNA-directed RNA polymerase II subunit RPB7 Neighboring gene Transporter Neighboring gene GPI ethanolamine phosphate transferase 1 Neighboring gene Ensconsin Neighboring gene Actin-related protein 2/3 complex subunit 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription factors regulating the fate and developmental potential of a multipotent progenitor in Caenorhabditis elegans. Soukup EM, et al. G3 (Bethesda), 2022 Nov 4. PMID 36063055, Free PMC Article
    2. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_491096.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3052048..3059165 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058695.8 → NP_491096.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491096.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3C6
      Conserved Domains (2) summary
      sd00017
      Location:279 → 299
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:291 → 317
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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