U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    acl-5 Phospholipid/glycerol acyltransferase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181241, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    acl-5
    Official Full Name
    Phospholipid/glycerol acyltransferase domain-containing protein
    Primary source
    WormBase:WBGene00011106
    Locus tag
    CELE_R07E3.5
    See related
    AllianceGenome:WB:WBGene00011106
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be involved in lipid metabolic process. Located in endoplasmic reticulum. Is expressed in body wall musculature and head. Orthologous to human GPAT3 (glycerol-3-phosphate acyltransferase 3) and GPAT4 (glycerol-3-phosphate acyltransferase 4). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See acl-5 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (10324163..10327456, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RING-type domain-containing protein Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene ADP/ATP translocase Neighboring gene Cuticlin-5 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Mitochondria-type GPAT is required for mitochondrial fusion. Ohba Y, et al. EMBO J, 2013 May 2. PMID 23572076, Free PMC Article
    2. Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Didiano D, et al. Nat Struct Mol Biol, 2006 Sep. PMID 16921378
    3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Phospholipid/glycerol acyltransferase domain-containing protein
    NP_001041282.1
    • Confirmed by transcript evidence
    NP_001041283.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10324163..10327456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047817.4 → NP_001041282.1  Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041282.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21812
      Conserved Domains (1) summary
      cl17185
      Location:68 → 444
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

    2. NM_001047818.4 → NP_001041283.1  Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041283.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ZXU8
      Conserved Domains (1) summary
      cl17185
      Location:11 → 387
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous