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    mcat-1 Malonyl-CoA:ACP transacylase (MAT) domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 259414, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mcat-1
    Official Full Name
    Malonyl-CoA:ACP transacylase (MAT) domain-containing protein
    Primary source
    WormBase:WBGene00016812
    Locus tag
    CELE_C50D2.9
    See related
    AllianceGenome:WB:WBGene00016812
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transferase activity. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT (malonyl-CoA-acyl carrier protein transacylase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mcat-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (88529..91519, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CPG4 domain-containing protein Neighboring gene putative ADP-dependent glucokinase Neighboring gene Luc7-like protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Malonyl-CoA:ACP transacylase (MAT) domain-containing protein
    NP_001367547.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      88529..91519 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381285.2 → NP_001367547.1  Malonyl-CoA:ACP transacylase (MAT) domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ITY6
      Conserved Domains (1) summary
      cl08282
      Location:94 → 396
      Acyl_transf_1; Acyl transferase domain
    Nucleotide Protein
    Heading Accession and Version

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