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    F40F9.10 tRNA wybutosine-synthesizing protein 2 homolog [ Caenorhabditis elegans ]

    Gene ID: 179363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F40F9.10
    Official Full Name
    tRNA wybutosine-synthesizing protein 2 homolog
    Primary source
    WormBase:WBGene00009586
    Locus tag
    CELE_F40F9.10
    See related
    AllianceGenome:WB:WBGene00009586
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation and wybutosine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in anal depressor muscle; body wall musculature; and pharynx. Orthologous to human TRMT12 (tRNA methyltransferase 12 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F40F9.10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (9711447..9713632, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein her-1 Neighboring gene Protein lifeguard 1-like Neighboring gene Transmembrane BAX inhibitor motif-containing protein 4 Neighboring gene PDZ domain-containing protein Neighboring gene ncRNA Neighboring gene Seven TM Receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in wybutosine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA wybutosine-synthesizing protein 2 homolog
    NP_505502.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9711447..9713632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073101.5 → NP_505502.2  tRNA wybutosine-synthesizing protein 2 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505502.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20240
      Conserved Domains (1) summary
      COG2520
      Location:31 → 255
      Trm5; tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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