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    cpx-2 ComPleXin (synaptic protein) homolog [ Caenorhabditis elegans ]

    Gene ID: 186917, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cpx-2
    Official Full Name
    ComPleXin (synaptic protein) homolog
    Primary source
    WormBase:WBGene00010520
    Locus tag
    CELE_K03A11.2
    See related
    AllianceGenome:WB:WBGene00010520
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis and neurotransmitter transport. Is expressed in coelomocyte and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cpx-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (13066974..13071220, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ShKT domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Homeobox protein ceh-28 Neighboring gene Sulfatase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes. Courtney KC, et al. Nat Struct Mol Biol, 2022 Feb. PMID 35132256, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ComPleXin (synaptic protein) homolog
    NP_001379153.1
    • Product from WormBase gene class cpx;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      13066974..13071220 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392868.1 → NP_001379153.1  ComPleXin (synaptic protein) homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21168
      Conserved Domains (1) summary
      pfam05835
      Location:1 → 54
      Synaphin; Synaphin protein
    Nucleotide Protein
    Heading Accession and Version

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