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    ins-32 INSulin related [ Caenorhabditis elegans ]

    Gene ID: 189403, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-32
    Official Full Name
    INSulin related
    Primary source
    WormBase:WBGene00002115
    Locus tag
    CELE_Y8A9A.6
    See related
    AllianceGenome:WB:WBGene00002115
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in intestine and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-32 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (3802959..3803319, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Flo11 domain-containing protein Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chronic vs acute manipulations reveal degeneracy in a thermosensory neuron network. Yeon J, et al. MicroPubl Biol, 2021 Jan 15. PMID 33474527, Free PMC Article
    2. Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling. Neal SJ, et al. Elife, 2015 Sep 3. PMID 26335407, Free PMC Article
    3. Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans. Peng JY, et al. Cell Rep, 2023 Jun 27. PMID 37289584
    4. Regulation of signaling genes by TGFbeta during entry into dauer diapause in C. elegans. Liu T, et al. BMC Dev Biol, 2004 Sep 20. PMID 15380030, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    INSulin related
    NP_494655.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      3802959..3803319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062254.3 → NP_494655.1  INSulin related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494655.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TYK2
      Conserved Domains (1) summary
      pfam03488
      Location:49 → 96
      Ins_beta; Nematode insulin-related peptide beta type
    Nucleotide Protein
    Heading Accession and Version

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