sec-8 Exocyst complex component 4 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: sec-8
Official Full Name: Exocyst complex component 4
Primary source: WormBase:WBGene00004753
Locus tag: CELE_Y106G6H.7
See related: AllianceGenome:WB:WBGene00004753
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in Golgi to plasma membrane transport; chemical synaptic transmission; and exocytosis. Predicted to be part of exocyst. Predicted to be active in growth cone membrane and synapse. Is expressed in embryonic cell; excretory canal; and hypodermis. Orthologous to human EXOC4 (exocyst complex component 4). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See sec-8 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 17

Sequence:: Chromosome: I; NC_003279.8 (10446657..10452075)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y106G6H.7 (e-PCR)
- UniSTS:312979

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in chemical synaptic transmission	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in exocytosis	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle docking involved in exocytosis	IEA Inferred from Electronic Annotation more info
involved_in vesicle tethering involved in exocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of exocyst	IBA Inferred from Biological aspect of Ancestor more info
part_of exocyst	IEA Inferred from Electronic Annotation more info
part_of exocyst	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in growth cone membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Exocyst complex component 4

NP_492732.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

10446657..10452075

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060331.9 → NP_492732.2 Exocyst complex component 4 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492732.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9XWS2

Conserved Domains (1) summary

pfam04048
Location:41 → 153

Sec8_exocyst; Sec8 exocyst complex component specific domain