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    dmd-6 DM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178392, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dmd-6
    Official Full Name
    DM domain-containing protein
    Primary source
    WormBase:WBGene00007058
    Locus tag
    CELE_F13G11.1
    See related
    AllianceGenome:WB:WBGene00007058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be active in nucleus. Is expressed in several structures, including intestine; neurons; pharynx; rectum; and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dmd-6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (14616603..14623961)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sex differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DM domain-containing protein
    NP_001255816.1
    • Confirmed by transcript evidence
    NP_001255817.1
    • Partially confirmed by transcript evidence
    NP_001370045.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      14616603..14623961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383245.2 → NP_001370045.1  DM domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62159
      Conserved Domains (1) summary
      smart00301
      Location:41 → 94
      DM; Doublesex DNA-binding motif

    2. NM_001268887.3 → NP_001255816.1  DM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT85
      Conserved Domains (1) summary
      pfam03154
      Location:113 → 333
      Atrophin-1; Atrophin-1 family

    3. NM_001268888.3 → NP_001255817.1  DM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255817.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT86
      Conserved Domains (1) summary
      pfam03154
      Location:94 → 314
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
    Heading Accession and Version

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