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    pigl-1 N-acetylglucosaminylphosphatidylinositol deacetylase [ Caenorhabditis elegans ]

    Gene ID: 3565275, updated on 9-Dec-2024

    Summary

    Official Symbol
    pigl-1
    Official Full Name
    N-acetylglucosaminylphosphatidylinositol deacetylase
    Primary source
    WormBase:WBGene00013131
    Locus tag
    CELE_Y52B11C.1
    See related
    AllianceGenome:WB:WBGene00013131
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable N-acetylglucosaminylphosphatidylinositol deacetylase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in CHIME syndrome. Orthologous to human PIGL (phosphatidylinositol glycan anchor biosynthesis class L). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See pigl-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (11163788..11168773, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene tRNA-Gly Neighboring gene Uncharacterized protein Neighboring gene Transmembrane protein 242 Neighboring gene ncRNA Neighboring gene PWI domain-containing protein

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum  

    General protein information

    Preferred Names
    N-acetylglucosaminylphosphatidylinositol deacetylase
    NP_001370270.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11163788..11168773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383729.2NP_001370270.1  N-acetylglucosaminylphosphatidylinositol deacetylase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      D4YWC2
      Conserved Domains (1) summary
      COG2120
      Location:27225
      LmbE; N-acetylglucosaminyl deacetylase, LmbE family [Carbohydrate transport and metabolism]
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