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    cpna-1 Copine family protein 1 [ Caenorhabditis elegans ]

    Gene ID: 173753, updated on 9-Dec-2024

    Summary

    Official Symbol
    cpna-1
    Official Full Name
    Copine family protein 1
    Primary source
    WormBase:WBGene00006495
    Locus tag
    CELE_F31D5.3
    See related
    AllianceGenome:WB:WBGene00006495
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables phosphatase binding activity and protein-macromolecule adaptor activity. Involved in positive regulation of sarcomere organization. Located in M band and striated muscle dense body. Is expressed in body wall musculature. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cpna-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (4186664..4208500)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene F-box associated domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene GPS domain-containing protein Neighboring gene GPS domain-containing protein Neighboring gene NfeD domain-containing protein Neighboring gene F-box domain-containing protein

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphatase binding PubMed 
    enables protein binding PubMed 
    enables protein-macromolecule adaptor activity PubMed 
    enables ubiquitin-protein transferase activity  
    Component Evidence Code Pubs
    located_in M band PubMed 
    located_in M band  
    located_in basal plasma membrane  
    located_in cytoplasm  
    is_active_in nucleus  
    located_in plasma membrane  
    located_in striated muscle dense body PubMed 

    General protein information

    Preferred Names
    Copine family protein 1
    NP_494736.1
    • Confirmed by transcript evidence
    NP_494737.1
    • Confirmed by transcript evidence
    NP_871985.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4186664..4208500
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_182185.6 → NP_871985.1  Copine family protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871985.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2KYS8
    2. NM_062336.6 → NP_494737.1  Copine family protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494737.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2KYS8
      Conserved Domains (1) summary
      cl00057
      Location:837 → 1062
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    3. NM_062335.8 → NP_494736.1  Copine family protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494736.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      H2KYS8, H2KYS9, H2KYT0, Q7JPE2
      Conserved Domains (1) summary
      cl00057
      Location:853 → 1078
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
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