memo-1 Protein MEMO1;Protein memo-1 homolog [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: memo-1
Official Full Name: Protein MEMO1;Protein memo-1 homolog
Primary source: WormBase:WBGene00016500
Locus tag: CELE_C37C3.8
See related: AllianceGenome:WB:WBGene00016500
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Is expressed in several structures, including gonad; intestine; neurons; vulva; and vulval precursor cell. Orthologous to human MEMO1 (mediator of cell motility 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See memo-1 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 8

Sequence:: Chromosome: V; NC_003283.11 (7844343..7847164, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Here, the authors identified the Caenorhabditis elegans orthologue of mammalian mediator of ErbB2-driven cell motility, MEMO-1, as a protein that inhibits BLI-3/NADPH oxidase.
Title: NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C37C3.8 (e-PCR)
- UniSTS:312209

Homology

Orthologs from OrthoDB

General protein information

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Preferred Names: Protein MEMO1;Protein memo-1 homolog

NP_001337309.1

Confirmed by transcript evidence

NP_001367638.1

Confirmed by transcript evidence

NP_001367639.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

7844343..7847164 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001380698.1 → NP_001367638.1 Protein memo-1 homolog [Caenorhabditis elegans]

Status: REVIEWED

Conserved Domains (1) summary

pfam01875
Location:12 → 281

Memo; Memo-like protein
NM_001350341.3 → NP_001337309.1 Protein MEMO1, partial [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1T5HUL2

Conserved Domains (1) summary

pfam01875
Location:98 → 367

Memo; Memo-like protein
NM_001380697.2 → NP_001367639.1 Protein memo-1 homolog [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q22915, Q8MPV4

Conserved Domains (1) summary

pfam01875
Location:60 → 329

Memo; Memo-like protein