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    tre-5 Trehalase [ Caenorhabditis elegans ]

    Gene ID: 173388, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tre-5
    Official Full Name
    Trehalase
    Primary source
    WormBase:WBGene00006611
    Locus tag
    CELE_C23H3.7
    See related
    AllianceGenome:WB:WBGene00006611
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Is expressed in head and hypodermis. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tre-5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (52997..55304, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene putative 26S proteasome regulatory subunit 10B Neighboring gene RNA polymerase I associated factor, A49-like protein Neighboring gene Nucleolus and neural progenitor protein-like N-terminal domain-containing protein Neighboring gene Serine palmitoyltransferase 1 Neighboring gene K Homology domain-containing protein Neighboring gene DUF3810 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trehalose metabolism genes in Caenorhabditis elegans and filarial nematodes. Pellerone FI, et al. Int J Parasitol, 2003 Sep 30. PMID 13678635
    2. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
    3. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha,alpha-trehalase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alpha,alpha-trehalase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in trehalose catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in trehalose metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Trehalase
    NP_493649.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      52997..55304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061248.5 → NP_493649.2  Trehalase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493649.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EG96
      Conserved Domains (1) summary
      cl17346
      Location:96 → 605
      Trehalase; Trehalase
    Nucleotide Protein
    Heading Accession and Version

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