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    fil-1 Lipase [ Caenorhabditis elegans ]

    Gene ID: 187940, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fil-1
    Official Full Name
    Lipase
    Primary source
    WormBase:WBGene00011321
    Locus tag
    CELE_T01C3.4
    See related
    AllianceGenome:WB:WBGene00011321
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables lipase activity. Involved in lipid catabolic process. Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See fil-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (14993838..14995207)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Transcription and mRNA export factor ENY2 Neighboring gene RING-type domain-containing protein Neighboring gene Receptor L-domain domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Toxic Effects of Size-tunable Gold Nanoparticles on Caenorhabditis elegans Development and Gene Regulation. Hu CC, et al. Sci Rep, 2018 Oct 15. PMID 30323250, Free PMC Article
    2. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Jo H, et al. Cell Metab, 2009 May. PMID 19416714
    3. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. Menzel R, et al. J Mol Biol, 2007 Jun 29. PMID 17499272
    4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lipid catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipase
    NP_506688.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14993838..14995207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074287.5 → NP_506688.1  Lipase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506688.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22060
      Conserved Domains (1) summary
      pfam01674
      Location:67 → 317
      Lipase_2; Lipase (class 2)
    Nucleotide Protein
    Heading Accession and Version

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