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    flp-13 SPSAVPLIRF-amide [ Caenorhabditis elegans ]

    Gene ID: 177547, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-13
    Official Full Name
    SPSAVPLIRF-amide
    Primary source
    WormBase:WBGene00001456
    Locus tag
    CELE_F33D4.3
    See related
    AllianceGenome:WB:WBGene00001456
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway; regulation of cellular response to heat; and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Is expressed in nerve ring; neurons; and spicule protractor muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-13 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (7696932..7698420, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Inositol 1,4,5-trisphosphate receptor itr-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Putative sphingolipid delta(4)-desaturase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. High-throughput, motility-based sorter for microswimmers such as C. elegans. Yuan J, et al. Lab Chip, 2015 Jul 7. PMID 26008643, Free PMC Article
    2. FMRFamide-like FLP-13 neuropeptides promote quiescence following heat stress in Caenorhabditis elegans. Nelson MD, et al. Curr Biol, 2014 Oct 20. PMID 25264253, Free PMC Article
    3. The RFamide receptor DMSR-1 regulates stress-induced sleep in C. elegans. Iannacone MJ, et al. Elife, 2017 Jan 17. PMID 28094002, Free PMC Article
    4. FRPR-4 Is a G-Protein Coupled Neuropeptide Receptor That Regulates Behavioral Quiescence and Posture in Caenorhabditis elegans. Nelson MD, et al. PLoS One, 2015. PMID 26571132, Free PMC Article
    5. Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans. Marks NJ, et al. Biochem Biophys Res Commun, 2001 Sep 7. PMID 11527423

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables neuropeptide receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of cellular response to heat IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of circadian sleep/wake cycle, sleep IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SPSAVPLIRF-amide
    NP_501255.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7696932..7698420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068854.5 → NP_501255.1  SPSAVPLIRF-amide [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501255.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O44185
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O44185.1

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