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    tbx-7 Putative T-box protein 7 [ Caenorhabditis elegans ]

    Gene ID: 260030, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tbx-7
    Official Full Name
    Putative T-box protein 7
    Primary source
    WormBase:WBGene00006544
    Locus tag
    CELE_ZK328.8
    See related
    AllianceGenome:WB:WBGene00006544
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tbx-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (6024958..6028532, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Tr-type G domain-containing protein Neighboring gene Nuclear pore complex protein Nup98 Neighboring gene ncRNA Neighboring gene Ubiquitin carboxyl-terminal hydrolase cyk-3 Neighboring gene ncRNA Neighboring gene putative F-box protein ZK328.6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans. Agulnik SI, et al. Genomics, 1995 Jan 1. PMID 7774921
    2. Three novel T-box genes in Caenorhabditis elegans. Agulnik SI, et al. Genome, 1997 Aug. PMID 9276934
    3. Role of T-box gene tbx-2 for anterior foregut muscle development in C. elegans. Smith PA, et al. Dev Biol, 2007 Feb 1. PMID 17005176, Free PMC Article
    4. C. elegans molting requires rhythmic accumulation of the Grainyhead/LSF transcription factor GRH-1. Meeuse MWM, et al. EMBO J, 2023 Feb 15. PMID 36688410, Free PMC Article
    5. A regulatory network of T-box genes and the even-skipped homologue vab-7 controls patterning and morphogenesis in C. elegans. Pocock R, et al. Development, 2004 May. PMID 15102704

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell fate specification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in developmental process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of transcription regulator complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Putative T-box protein 7
    NP_001368539.1
    • Confirmed by transcript evidence
    NP_001368540.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6024958..6028532 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379739.1 → NP_001368539.1  Putative T-box protein 7 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam00907
      Location:30 → 209
      T-box

    2. NM_001379738.1 → NP_001368540.1  Putative T-box protein 7 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0K3ARF9, A0A0K3AUZ0, Q23467, Q95PX3
      Conserved Domains (1) summary
      pfam00907
      Location:66 → 245
      T-box
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95PX3.2

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