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    col-36 Cuticle collagen 36 [ Caenorhabditis elegans ]

    Gene ID: 174178, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-36
    Official Full Name
    Cuticle collagen 36
    Primary source
    WormBase:WBGene00000613
    Locus tag
    CELE_C27H5.5
    See related
    AllianceGenome:WB:WBGene00000613
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be part of collagen trimer. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human COL21A1 (collagen type XXI alpha 1 chain). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-36 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (7167511..7168812, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ferrochelatase Neighboring gene Transmembrane protein 180 Neighboring gene Intraflagellar transport protein 56 homolog Neighboring gene ncRNA Neighboring gene Glutamate-gated ChLoride channel

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification, sequence and expression patterns of the Caenorhabditis elegans col-36 and col-40 collagen-encoding genes. Levy AD, et al. Gene, 1993 Dec 31. PMID 8299960
    2. Differential gene expression of Caenorhabditis elegans grown on unmethylated sterols or 4alpha-methylsterols. Merris M, et al. J Lipid Res, 2007 May. PMID 17277379
    3. The cuticle of the nematode Caenorhabditis elegans: a complex collagen structure. Johnstone IL. Bioessays, 1994 Mar. PMID 8166670
    4. Analysis of mutations in the sqt-1 and rol-6 collagen genes of Caenorhabditis elegans. Kramer JM, et al. Genetics, 1993 Dec. PMID 8307321, Free PMC Article
    5. Structures and functions of collagens in Caenorhabditis elegans. Kramer JM. FASEB J, 1994 Mar 1. PMID 8143939

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticle collagen 36
    NP_495487.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7167511..7168812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063086.6 → NP_495487.1  Cuticle collagen 36 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495487.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34803
      Conserved Domains (1) summary
      smart01088
      Location:15 → 67
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34803.1

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