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    ugt-50 Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 181413, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-50
    Official Full Name
    Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase
    Primary source
    WormBase:WBGene00011564
    Locus tag
    CELE_T07C5.1
    See related
    AllianceGenome:WB:WBGene00011564
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is expressed in PVQ; intestine; and lateral ganglion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-50 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (12691573..12695652)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene A disintegrin and metalloproteinase with thrombospondin motifs adt-1;Peptidase M12B domain-containing protein Neighboring gene ncRNA Neighboring gene Nuclear receptor domain-containing protein Neighboring gene pseudo Neighboring gene Nuclear Hormone Receptor family Neighboring gene Nuclear Hormone Receptor family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes. Hellwig S, et al. Proc Natl Acad Sci U S A, 2008 Sep 2. PMID 18723671, Free PMC Article
    2. Identification of CED-3 substrates by a yeast-based screening method. Kim SY, et al. Mol Biotechnol, 2004 May. PMID 15122042
    3. Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction. Chamoli M, et al. Nat Commun, 2020 Sep 25. PMID 32978396, Free PMC Article
    4. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative UDP-glucuronosyltransferase ugt-50;UDP-glucuronosyltransferase;glucuronosyltransferase
    NP_001300379.1
    • Confirmed by transcript evidence
    NP_001300380.1
    • Confirmed by transcript evidence
    NP_001359531.1
    • Confirmed by transcript evidence
    NP_741913.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12691573..12695652
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373541.1 → NP_001359531.1  Putative UDP-glucuronosyltransferase ugt-50 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cl10013
      Location:26 → 169
      Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology

    2. NM_001313451.3 → NP_001300380.1  glucuronosyltransferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ATD5
      Conserved Domains (1) summary
      cl10013
      Location:9 → 144
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...

    3. NM_171786.8 → NP_741913.1  Putative UDP-glucuronosyltransferase ugt-50 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741913.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O62371, Q22295, Q8MPX8
      Conserved Domains (2) summary
      PHA03392
      Location:9 → 475
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:26 → 520
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    4. NM_001313450.3 → NP_001300379.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AYM2
      Conserved Domains (1) summary
      PHA03392
      Location:130 → 376
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q22295.2

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