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    ppp1r13l protein phosphatase 1, regulatory subunit 13 like [ Danio rerio (zebrafish) ]

    Gene ID: 541507, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ppp1r13lprovided by ZNC
    Official Full Name
    protein phosphatase 1, regulatory subunit 13 likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050327-33
    See related
    Ensembl:ENSDARG00000013777 AllianceGenome:ZFIN:ZDB-GENE-050327-33
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:113058
    Summary
    Predicted to be involved in positive regulation of cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Orthologous to human PPP1R13L (protein phosphatase 1 regulatory subunit 13 like). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See ppp1r13l in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (35842934..35898821)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (35861922..35917877)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein U-like 1 Neighboring gene outer mitochondrial membrane lipid metabolism regulator OPA3 Neighboring gene uncharacterized LOC137488315 Neighboring gene transmembrane protein 91 Neighboring gene exosome component 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Modeling Sarcoglycanopathy in Danio rerio. Dalla Barba F, et al. Int J Mol Sci, 2023 Aug 11. PMID 37628888, Free PMC Article
    2. Phylogenetic and Expression Analysis of Fos Transcription Factors in Zebrafish. Kubra K, et al. Int J Mol Sci, 2022 Sep 3. PMID 36077499, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in positive regulation of cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    relA-associated inhibitor
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 13 like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014320.2 → NP_001014342.1  relA-associated inhibitor

      See identical proteins and their annotated locations for NP_001014342.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091786
      UniProtKB/TrEMBL
      Q58ER8
      Related
      ENSDARP00000126054.1, ENSDART00000151587.3
      Conserved Domains (5) summary
      cd11952
      Location:720 → 774
      SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
      cd00204
      Location:594 → 689
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:564 → 649
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:621 → 672
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:585 → 616
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      35842934..35898821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173644.5 → XP_005173701.1  relA-associated inhibitor isoform X1

      See identical proteins and their annotated locations for XP_005173701.1

      UniProtKB/TrEMBL
      A0A8M2BKW6, Q1L9A3
      Related
      ENSDARP00000106399.2, ENSDART00000131121.3
      Conserved Domains (5) summary
      cd11952
      Location:725 → 779
      SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
      cd00204
      Location:599 → 694
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:569 → 654
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:626 → 677
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:590 → 621
      ANK; ANK repeat [structural motif]

    2. XM_005173643.5 → XP_005173700.1  relA-associated inhibitor isoform X1

      See identical proteins and their annotated locations for XP_005173700.1

      UniProtKB/TrEMBL
      A0A8M2BKW6, Q1L9A3
      Conserved Domains (5) summary
      cd11952
      Location:725 → 779
      SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
      cd00204
      Location:599 → 694
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:569 → 654
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:626 → 677
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:590 → 621
      ANK; ANK repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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