bzw1b basic leucine zipper and W2 domains 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: bzw1bprovided by ZNC
Official Full Name: basic leucine zipper and W2 domains 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-2881
See related: Ensembl:ENSDARG00000099148 AllianceGenome:ZFIN:ZDB-GENE-040426-2881
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: bzw1l; zgc:55457; zgc:76909; wu:fb19e02; zgc:110545; ik:tdsubc_1g3; xx:tdsubc_1g3
Summary: Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm. Is expressed in gill; heart; intestine; kidney; and spleen. Orthologous to human BZW1 (basic leucine zipper and W2 domains 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 9

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	9	NC_007120.7 (426410..433912)
105	previous assembly	GRCz10 (GCF_000002035.5)	9	NC_007120.6 (426749..434282)

Chromosome 9 - NC_007120.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb19e02.x1 (e-PCR)
- UniSTS:190260

fb19e02.x1 (e-PCR)
- UniSTS:190261

G47501 (e-PCR)
- UniSTS:108277

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in regulation of translational initiation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: eIF5-mimic protein 2-B

Names: basic leucine zipper and W2 domain-containing protein 1-B; basic leucine zipper and W2 domains 1, like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213092.1 → NP_998257.1 eIF5-mimic protein 2-B

See identical proteins and their annotated locations for NP_998257.1

Status: PROVISIONAL

Source sequence(s)

BC066527

UniProtKB/Swiss-Prot

Q58ED0, Q6NYN0, Q803N9

UniProtKB/TrEMBL

A0A0R4IMX3

Conserved Domains (1) summary

cd11560
Location:217 → 407

W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins