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    Stt3B Catalytic subunit 3B of the oligosaccharyltransferase complex [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43005, updated on 9-Dec-2024

    Summary

    Official Symbol
    Stt3Bprovided by FlyBase
    Official Full Name
    Catalytic subunit 3B of the oligosaccharyltransferase complexprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011336
    Locus tag
    Dmel_CG7748
    See related
    AllianceGenome:FB:FBgn0011336
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO03054008.7; BcDNA.GM01838; BcDNA:GM01838; CG7748; Dmel\CG7748; l(3)j2D9; OstStt3; STT
    Summary
    Predicted to enable dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in post-translational protein modification and protein N-linked glycosylation via asparagine. Located in endomembrane system. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; ganglia; gut section; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ix. Orthologous to human STT3B (STT3 oligosaccharyltransferase complex catalytic subunit B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Stt3B in Genome Data Viewer
    Location:
    96B19-96B20; 3-86 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25066712..25069637, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20892434..20895359, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene staccato Neighboring gene veli Neighboring gene Poly-glutamine tract binding protein 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dolichyl-diphosphooligosaccharide-protein glycotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables oligosaccharyl transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in post-translational protein modification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation via asparagine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of oligosaccharyltransferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    catalytic subunit 3B of the oligosaccharyltransferase complex
    Names
    CG7748-PA
    Stt3B-PA
    oligosaccharyl transferase 3
    NP_524494.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25066712..25069637 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079770.3NP_524494.1  catalytic subunit 3B of the oligosaccharyltransferase complex [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524494.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KN63, Q9XZ53
      Related
      FBpp0084161
      Conserved Domains (2) summary
      COG1287
      Location:10768
      Stt3; Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones]
      pfam02516
      Location:18514
      STT3; Oligosaccharyl transferase STT3 subunit