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    I-t inhibitor-t [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41414, updated on 9-Dec-2024

    Summary

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    Official Symbol
    I-tprovided by FlyBase
    Official Full Name
    inhibitor-tprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025821
    Locus tag
    Dmel_CG14719
    See related
    AllianceGenome:FB:FBgn0025821
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14719; Dmel\CG14719; pp1d6
    Summary
    Enables protein phosphatase inhibitor activity. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See I-t in Genome Data Viewer
    Location:
    86E16-86E16; 3-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (11704030..11704916)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7529752..7530638)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46011 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterisation of a novel Drosophila melanogaster testis specific PP1 inhibitor related to mammalian inhibitor-2: identification of the site of interaction with PP1. Helps NR, et al. FEBS Lett, 1998 Oct 30. PMID 9821974
    2. Seizure suppression through manipulating splicing of a voltage-gated sodium channel. Lin WH, et al. Brain, 2015 Apr. PMID 25681415, Free PMC Article
    3. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
    4. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibitor-t
    Names
    CG14719-PA
    I-t-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      11704030..11704916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079599.4 → NP_524323.2  inhibitor-t [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524323.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O96723, Q9VGJ2
      Related
      FBpp0081903
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O96723 O96723
    Q9VGJ2 Q9VGJ2

    Gene LinkOut

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