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    CG34367 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740879, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34367provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085396
    Locus tag
    Dmel_CG34367
    See related
    AllianceGenome:FB:FBgn0085396
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13141; CG5369; Dmel\CG34367
    Old locus tag
    CG13141; CG5369; Dmel_CG13141; Dmel_CG5369
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Leri-Weill dyschondrosteosis; SHOX-related short stature; and lung cancer. Orthologous to several human genes including SHOX (SHOX homeobox). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34367 in Genome Data Viewer
    Location:
    31D9-31D10; 2-41 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10347851..10353905, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10347851..10353905, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Selenophosphate synthetase 2 Neighboring gene FERM domain containing Neighboring gene Cathepsin L4 Neighboring gene Caseinolytic protease proteolytic subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of larval and adult Drosophila astrocytes reveals stage-specific gene expression profiles. Huang Y, et al. G3 (Bethesda), 2015 Feb 4. PMID 25653313, Free PMC Article
    2. A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain. Davie K, et al. Cell, 2018 Aug 9. PMID 29909982, Free PMC Article
    3. RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides. Abruzzi KC, et al. PLoS Genet, 2017 Feb. PMID 28182648, Free PMC Article
    4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    5. Homeodomain proteins: an update. Bürglin TR, et al. Chromosoma, 2016 Jun. PMID 26464018, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34367-PB
    CG34367-PC
    CG34367-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10347851..10353905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103670.3 → NP_001097140.1  uncharacterized protein Dmel_CG34367, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097140.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DYR8
      Conserved Domains (2) summary
      pfam00046
      Location:195 → 248
      Homeobox; Homeobox domain
      pfam03826
      Location:392 → 409
      OAR; OAR domain

    2. NM_001273402.1 → NP_001260331.1  uncharacterized protein Dmel_CG34367, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260331.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCS1
      Conserved Domains (1) summary
      pfam00046
      Location:72 → 114
      Homeobox; Homeobox domain

    3. NM_001169463.1 → NP_001162934.1  uncharacterized protein Dmel_CG34367, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162934.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A2RVG7
      Conserved Domains (2) summary
      pfam00046
      Location:72 → 125
      Homeobox; Homeobox domain
      pfam03826
      Location:269 → 286
      OAR; OAR domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2RVG7 A2RVG7
    A8DYR8 A8DYR8
    M9PCS1 M9PCS1

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