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    atos atossa [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36243, updated on 9-Dec-2024

    Summary

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    Official Symbol
    atosprovided by FlyBase
    Official Full Name
    atossaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033638
    Locus tag
    Dmel_CG9005
    See related
    AllianceGenome:FB:FBgn0033638
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH05710; CG9005; Dmel\CG9005; mda
    Summary
    Involved in positive regulation of gene expression. Is active in nucleus. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; apoptotic amnioserosa; embryonic/larval midgut primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See atos in Genome Data Viewer
    Location:
    48A3-48B2; 2-64 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11619479..11640941, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7506984..7528446, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43907 Neighboring gene Enigma Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Mourikis P, et al. Proc Natl Acad Sci U S A, 2006 Jan 31. PMID 16434470, Free PMC Article
    2. Are entrenched characters developmentally constrained? Creating biramous limbs in an insect. Dworkin IM, et al. Evol Dev, 2001 Nov-Dec. PMID 11806638
    3. A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response. Hilsabeck TAU, et al. Geroscience, 2022 Aug. PMID 35381951, Free PMC Article
    4. Enhancer-promoter communication at the Drosophila engrailed locus. Kwon D, et al. Development, 2009 Sep. PMID 19675130, Free PMC Article
    5. Using natural variation in Drosophila to discover previously unknown endoplasmic reticulum stress genes. Chow CY, et al. Proc Natl Acad Sci U S A, 2013 May 28. PMID 23667151, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of positive regulation of oxidative phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to endoplasmic reticulum stress HMP PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    atossa
    Names
    CG9005-PA
    CG9005-PB
    CG9005-PC
    CG9005-PE
    atos-PA
    atos-PB
    atos-PC
    atos-PE
    medusa

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11619479..11640941 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169647.3 → NP_001163118.1  atossa, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163118.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JXG9
      Conserved Domains (2) summary
      pfam13889
      Location:1226 → 1290
      Chromosome_seg; Chromosome segregation during meiosis
      pfam13915
      Location:1074 → 1132
      DUF4210; Domain of unknown function (DUF4210)

    2. NM_001382201.1 → NP_001369081.1  atossa, isoform E [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A6M3Q835
      Conserved Domains (2) summary
      pfam13889
      Location:1226 → 1290
      Chromosome_seg; Chromosome segregation during meiosis
      pfam13915
      Location:1074 → 1131
      DUF4210; Domain of unknown function (DUF4210)

    3. NM_001259338.3 → NP_001246267.1  atossa, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246267.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JXG9
      Conserved Domains (2) summary
      pfam13889
      Location:1226 → 1290
      Chromosome_seg; Chromosome segregation during meiosis
      pfam13915
      Location:1074 → 1132
      DUF4210; Domain of unknown function (DUF4210)

    4. NM_136844.4 → NP_610688.1  atossa, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610688.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JXG9
      Related
      FBpp0087191
      Conserved Domains (2) summary
      pfam13889
      Location:1226 → 1290
      Chromosome_seg; Chromosome segregation during meiosis
      pfam13915
      Location:1074 → 1132
      DUF4210; Domain of unknown function (DUF4210)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A6M3Q835 A0A6M3Q835
    Q7JXG9.1 Q7JXG9

    Gene LinkOut

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