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    CG13531 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37627, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG13531provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034786
    Locus tag
    Dmel_CG13531
    See related
    AllianceGenome:FB:FBgn0034786
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13531
    Summary
    Predicted to be involved in several processes, including axo-dendritic transport; axon extension; and synaptic vesicle transport. Predicted to be active in several cellular components, including axon; dendrite; and synapse. Is expressed in adult head. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG13531 in Genome Data Viewer
    Location:
    59B2-59B3; 2-101 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22847832..22853827, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18735355..18741350, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L23 Neighboring gene inactivation no afterpotential D Neighboring gene forkhead domain 59A

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in axo-dendritic transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in axon extension ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic vesicle transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG13531-PB
    CG13531-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22847832..22853827 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299819.1NP_001286748.1  uncharacterized protein Dmel_CG13531, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286748.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1Y8
      Conserved Domains (1) summary
      pfam14649
      Location:14521746
      Spatacsin_C; Spatacsin C-terminus
    2. NM_137882.2NP_611726.1  uncharacterized protein Dmel_CG13531, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611726.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1Y8
      Related
      FBpp0071821
      Conserved Domains (1) summary
      pfam14649
      Location:14521746
      Spatacsin_C; Spatacsin C-terminus