U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Pop4 POP4 ribonuclease P/MRP subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38889, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Pop4provided by FlyBase
    Official Full Name
    POP4 ribonuclease P/MRP subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035831
    Locus tag
    Dmel_CG8038
    See related
    AllianceGenome:FB:FBgn0035831
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.38; BcDNA:LD45688; CG8038; Dmel\CG8038; Rpp29
    Summary
    Predicted to enable rRNA primary transcript binding activity and ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Pop4 in Genome Data Viewer
    Location:
    66A21-66A22; 3-21 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7977805..7978650, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7970905..7971750, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ribonuclease X25 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Heterochromatin protein 4 Neighboring gene nemo Neighboring gene transfer RNA:Alanine-AGC 2-1 Neighboring gene antisense RNA:CR45867 Neighboring gene bip1

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits. Palsule G, et al. Nucleic Acids Res, 2019 Sep 19. PMID 31287870, Free PMC Article
    2. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article
    3. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. Mohr SE, et al. G3 (Bethesda), 2015 Jul 21. PMID 26199285, Free PMC Article
    4. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables rRNA primary transcript binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ribonuclease P RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribonuclease P RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of nucleolar ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonuclease MRP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    POP4 ribonuclease P/MRP subunit
    Names
    CG8038-PA
    Pop4-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7977805..7978650 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139911.3 → NP_648168.1  POP4 ribonuclease P/MRP subunit [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648168.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C4XVM6, Q9VSC6
      Related
      FBpp0076478
      Conserved Domains (1) summary
      smart00538
      Location:111 → 201
      POP4; A domain found in a protein subunit of human RNase MRP and RNase P ribonucleoprotein complexes and archaeal proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSA7 Q8MSA7
    Q9VSC6 Q9VSC6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools