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    eIF3l eukaryotic translation initiation factor 3 subunit l [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39386, updated on 9-Dec-2024

    Summary

    Official Symbol
    eIF3lprovided by FlyBase
    Official Full Name
    eukaryotic translation initiation factor 3 subunit lprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036258
    Locus tag
    Dmel_CG5642
    See related
    AllianceGenome:FB:FBgn0036258
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5642; Dmel\CG5642
    Summary
    Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol. Is expressed in adult head; adult heart; and organism. Orthologous to human EIF3L (eukaryotic translation initiation factor 3 subunit L). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See eIF3l in Genome Data Viewer
    Location:
    68F6-68F6; 3-38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12143446..12146097, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12136546..12139197, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) SGDH subunit Neighboring gene Autophagy-related 12 Neighboring gene Rho GTPase activating protein at 68F Neighboring gene Neurexin IV Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to translation initiation factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translational initiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol HDA PubMed 
    part_of eukaryotic translation initiation factor 3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of eukaryotic translation initiation factor 3 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of eukaryotic translation initiation factor 3 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit l
    Names
    CG5642-PA
    eIF3l-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12143446..12146097 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140296.3NP_648553.1  eukaryotic translation initiation factor 3 subunit l [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648553.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VTU4
      Related
      FBpp0075754
      Conserved Domains (1) summary
      pfam10255
      Location:122527
      Paf67; RNA polymerase I-associated factor PAF67