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    CG10584 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40324, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10584provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037045
    Locus tag
    Dmel_CG10584
    See related
    AllianceGenome:FB:FBgn0037045
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.713; Dmel\CG10584; METTL22
    Summary
    Predicted to enable protein methyltransferase activity. Predicted to be active in nucleus. Orthologous to human METTL22 (methyltransferase 22, Kin17 lysine). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10584 in Genome Data Viewer
    Location:
    78A2-78A5; 3-47 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21030280..21031360, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21023380..21024460, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene small Cajal body-specific RNA : PsiU6-40 Neighboring gene skuld Neighboring gene antisense RNA:CR45801 Neighboring gene Decaprenyl diphosphate synthase subunit 2 Neighboring gene RNA polymerase III subunit E Neighboring gene uncharacterized protein Neighboring gene schizo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    2. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article
    3. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    4. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in protein methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10584-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21030280..21031360 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141021.2 → NP_649278.1  uncharacterized protein Dmel_CG10584 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VP86
      Related
      FBpp0077983
      Conserved Domains (1) summary
      cl17173
      Location:70 → 219
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VP86 Q9VP86

    Gene LinkOut

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