U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tim17b1 Tim17b1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40635, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Tim17b1provided by FlyBase
    Official Full Name
    Tim17b1provided by FlyBase
    Primary source
    FLYBASE:FBgn0037310
    Locus tag
    Dmel_CG1158
    See related
    AllianceGenome:FB:FBgn0037310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT16284; CG1158; Dmel\CG1158
    Summary
    Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in organism. Orthologous to human TIMM17A (translocase of inner mitochondrial membrane 17A) and TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Tim17b1 in Genome Data Viewer
    Location:
    82F8-82F9; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5300145..5301186)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1125867..1126908)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene HIF prolyl hydroxylase Neighboring gene pseudo Neighboring gene mustard Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Generating a knockdown transgene against Drosophila heterochromatic Tim17b gene encoding mitochondrial translocase subunit. Garabedian M, et al. PLoS One, 2011. PMID 21998726, Free PMC Article
    2. Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Sun LV, et al. Proc Natl Acad Sci U S A, 2003 Aug 5. PMID 12876199, Free PMC Article
    3. Evolution of the Tim17 protein family. Žárský V, et al. Biol Direct, 2016 Oct 19. PMID 27760563, Free PMC Article
    4. Genomic signatures of globally enhanced gene duplicate accumulation in the megadiverse higher Diptera fueling intralocus sexual conflict resolution. Bao R, et al. PeerJ, 2020. PMID 33083121, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to protein transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in protein insertion into mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Tim17b1
    Names
    CG1158-PA
    Tim17b1-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5300145..5301186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141269.3 → NP_649526.2  Tim17b1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649526.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1A730, Q8MZB4, Q9VNA0
      Related
      FBpp0078430
      Conserved Domains (1) summary
      cl02381
      Location:1 → 147
      Tim17; Tim17/Tim22/Tim23/Pmp24 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNA0.2 Q9VNA0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous