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    Ir85a Ionotropic receptor 85a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41052, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ir85aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 85aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037630
    Locus tag
    Dmel_CG11775
    See related
    AllianceGenome:FB:FBgn0037630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    85a; CG11775; CT32618; DmelIR85a; Dmel\CG11775; IR85a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in larval abdomen. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir85a in Genome Data Viewer
    Location:
    85B1-85B1; 3-48 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8794684..8796966)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4620406..4622688)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene PFTAIRE-interacting factor 1B Neighboring gene PFTAIRE-interacting factor 1A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chaperonin containing TCP1 subunit 7 Neighboring gene uncharacterized protein Neighboring gene hinge2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic and functional genetic evidence for distinct ecophysiological responses across complex life cycle stages. Freda PJ, et al. J Exp Biol, 2022 Jun 1. PMID 35578907
    2. Genetic variation in the shape of cold-survival curves in a single fly population suggests potential for selection from climate variability. Teets NM, et al. J Evol Biol, 2018 Apr. PMID 29345010
    3. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Lee JY, et al. Comp Biochem Physiol C Toxicol Pharmacol, 2009 Nov. PMID 19695344
    4. A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster. Sang J, et al. Elife, 2024 Apr 4. PMID 38573740, Free PMC Article
    5. Avoiding cantharidin through ionotropic receptors. Pradhan RN, et al. J Hazard Mater, 2024 Mar 15. PMID 38278077

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 85a
    Names
    CG11775-PA
    Ir85a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8794684..8796966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141576.2 → NP_649833.1  ionotropic receptor 85a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649833.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3YDL3, Q9VHL4
      Related
      FBpp0081400
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHL4 Q9VHL4

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