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    CG9386 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9386provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037708
    Locus tag
    Dmel_CG9386
    See related
    AllianceGenome:FB:FBgn0037708
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9386; METTL19
    Summary
    Predicted to enable tRNA (uridine) methyltransferase activity. Predicted to be involved in tRNA methylation. Is expressed in embryonic/larval midgut; larval muscle system; and organism. Orthologous to human TRMT44 (tRNA methyltransferase 44 homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9386 in Genome Data Viewer
    Location:
    85D24-85D24; 3-48 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9553696..9555408, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5379418..5381130, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene blistery Neighboring gene murashka Neighboring gene long non-coding RNA:CR42549 Neighboring gene RNA-binding protein S1 Neighboring gene Branched chain keto acid dehydrogenase E1 subunit alpha Neighboring gene Adaptor Protein complex 1, mu subunit Neighboring gene Methyl-CpG binding domain protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. dTrmt10A impacts Hsp70 chaperone m(6)A levels and the stress response in the Drosophila brain. Perlegos AE, et al. Sci Rep, 2023 Dec 28. PMID 38155219, Free PMC Article
    2. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    3. H/ACA snRNP-dependent ribosome biogenesis regulates translation of polyglutamine proteins. Breznak SM, et al. Sci Adv, 2023 Jun 23. PMID 37343092, Free PMC Article
    4. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    5. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA (uridine) methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9386-PA
    NP_649904.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9553696..9555408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141647.5 → NP_649904.2  uncharacterized protein Dmel_CG9386 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649904.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VHB9
      Conserved Domains (1) summary
      pfam07757
      Location:153 → 265
      AdoMet_MTase; Predicted AdoMet-dependent methyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VHB9.2 Q9VHB9

    Gene LinkOut

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