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    RpL6 Ribosomal protein L6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43723, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RpL6provided by FlyBase
    Official Full Name
    Ribosomal protein L6provided by FlyBase
    Primary source
    FLYBASE:FBgn0039857
    Locus tag
    Dmel_CG11522
    See related
    AllianceGenome:FB:FBgn0039857
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11522; Dmel\CG11522; L6e; Rp L6; rpl6; RPL6
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Orthologous to human RPL6 (ribosomal protein L6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See RpL6 in Genome Data Viewer
    Location:
    100C7-100C7; 3-102 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31594792..31596204, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (27420514..27421926, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cyclin G Neighboring gene Medea Neighboring gene microtubule-associated Nat9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila vigilin, DDP1, localises to the cytoplasm and associates to the rough endoplasmic reticulum. Batlle M, et al. Biochim Biophys Acta, 2011 Jan. PMID 21035573
    2. Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis. Fouix S, et al. Genes Cells, 2003 Nov. PMID 14622141
    3. Srlp is crucial for the self-renewal and differentiation of germline stem cells via RpL6 signals in Drosophila testes. Yu J, et al. Cell Death Dis, 2019 Apr 1. PMID 30931935, Free PMC Article
    4. Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila. Yu J, et al. FASEB J, 2019 Jul. PMID 30921522
    5. RpS13 controls the homeostasis of germline stem cell niche through Rho1-mediated signals in the Drosophila testis. Wang M, et al. Cell Prolif, 2020 Oct. PMID 32896929, Free PMC Article

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L6
    Names
    CG11522-PA
    CG11522-PB
    RpL6-PA
    RpL6-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      31594792..31596204 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170554.2 → NP_733433.1  ribosomal protein L6, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733433.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9W2
      Related
      FBpp0085165
      Conserved Domains (1) summary
      cd13156
      Location:87 → 243
      KOW_RPL6; KOW motif of Ribosomal Protein L6

    2. NM_143619.3 → NP_651876.1  ribosomal protein L6, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651876.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V9W3
      Related
      FBpp0085166
      Conserved Domains (3) summary
      COG2163
      Location:111 → 234
      RPL14A; Ribosomal protein L14E/L6E/L27E [Translation, ribosomal structure and biogenesis]
      cd13156
      Location:106 → 262
      KOW_RPL6; KOW motif of Ribosomal Protein L6
      pfam03868
      Location:23 → 51
      Ribosomal_L6e_N; Ribosomal protein L6, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V9W2 Q9V9W2
    Q9V9W3 Q9V9W3

    Gene LinkOut

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