CG8128 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG8128provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0030668
Locus tag: Dmel_CG8128
See related: AllianceGenome:FB:FBgn0030668
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG8128
Summary: Predicted to enable ADP-ribose diphosphatase activity; NAD binding activity; and NADH pyrophosphatase activity. Is expressed in adult head. Orthologous to human NUDT6 (nudix hydrolase 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 13E7-13E8; 1-51 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (15697494..15700034)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (15591527..15594067)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables ADP-ribose diphosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables NAD binding	IBA Inferred from Biological aspect of Ancestor more info
enables NADH pyrophosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables NADH pyrophosphatase activity	ISS Inferred from Sequence or Structural Similarity more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: uncharacterized protein

Names: CG8128-PA; CG8128-PB

NP_001285282.1

EC 3.-.-.-

EC 3.6.1.13

EC 3.6.1.22

NP_573053.2

EC 3.-.-.-

EC 3.6.1.13

EC 3.6.1.22

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

15697494..15700034

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_132825.4 → NP_573053.2 uncharacterized protein Dmel_CG8128, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_573053.2

Status: REVIEWED

UniProtKB/TrEMBL

Q961V9, Q9VXR9

Related

FBpp0073869

Conserved Domains (1) summary

cd04670
Location:159 → 287

Nudix_Hydrolase_12; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
NM_001298353.1 → NP_001285282.1 uncharacterized protein Dmel_CG8128, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285282.1

Status: REVIEWED

UniProtKB/TrEMBL

Q961V9, Q9VXR9

Conserved Domains (1) summary

cd04670
Location:159 → 287

Nudix_Hydrolase_12; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...