wal walrus [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: walprovided by FlyBase
Official Full Name: walrusprovided by FlyBase
Primary source: FLYBASE:FBgn0010516
Locus tag: Dmel_CG8996
See related: AllianceGenome:FB:FBgn0010516
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA.LD07532; BcDNA:GH09945; BcDNA:LD07532; CG8996; Dmel\CG8996; EP2253; Etf; ETF; ETFA; l(2)02516; P447
Summary: Predicted to enable electron transfer activity and flavin adenine dinucleotide binding activity. Involved in digestive tract morphogenesis; head involution; and open tracheal system development. Predicted to be active in mitochondrion. Is expressed in several structures, including adult brain; adult central complex; embryonic/larval midgut primordium; larval muscle cell; and mesoderm. Human ortholog(s) of this gene implicated in multiple acyl-CoA dehydrogenase deficiency. Orthologous to human ETFA (electron transfer flavoprotein subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (11688569..11690863, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (7576074..7578368, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables electron transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables electron transfer activity	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	ISS Inferred from Sequence or Structural Similarity more info
enables flavin adenine dinucleotide binding	IBA Inferred from Biological aspect of Ancestor more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Malpighian tubule morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in ectodermal digestive tract morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	ISS Inferred from Sequence or Structural Similarity more info
involved_in head involution	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in morphogenesis of an epithelium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in open tracheal system development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

Names: CG8996-PA; CG8996-PB; electron transfer flavoprotein; electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha-subunit; wal-PA; wal-PB

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