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    Tdh L-threonine dehydrogenase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40268, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tdhprovided by FlyBase
    Official Full Name
    L-threonine dehydrogenaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036997
    Locus tag
    Dmel_CG5955
    See related
    AllianceGenome:FB:FBgn0036997
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5955; Dmel\CG5955
    Summary
    Predicted to enable L-threonine 3-dehydrogenase activity. Predicted to be involved in threonine catabolic process. Is expressed in adult head. Orthologous to human TDH (L-threonine dehydrogenase (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tdh in Genome Data Viewer
    Location:
    77C4-77C4; 3-47 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20466944..20469592)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20460044..20462692)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene artichoke Neighboring gene magro Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene iso Glutaminyl cyclase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-threonine 3-dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in threonine catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L-threonine dehydrogenase
    Names
    CG5955-PA
    L-threonine 3-dehydrogenase, mitochondrial
    Tdh-PA
    NP_649230.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20466944..20469592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140973.3 → NP_649230.1  L-threonine dehydrogenase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649230.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VPE8
      Related
      FBpp0077855
      Conserved Domains (2) summary
      cd05272
      Location:47 → 351
      TDH_SDR_e; L-threonine dehydrogenase, extended (e) SDRs
      COG0451
      Location:47 → 355
      WcaG; Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VPE8 Q9VPE8

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