mRpL50 mitochondrial ribosomal protein L50 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mRpL50provided by FlyBase
Official Full Name: mitochondrial ribosomal protein L50provided by FlyBase
Primary source: FLYBASE:FBgn0028648
Locus tag: Dmel_CG8612
See related: AllianceGenome:FB:FBgn0028648
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-65Eb; ANON-65Eb; BcDNA:GM06185; BcDNA:RE06140; CG8612; Dmel\CG8612; MRP-L50
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in adult heart and organism. Used to study primary ovarian insufficiency. Orthologous to human MRPL50 (mitochondrial ribosomal protein L50). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (7243080..7243933, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (7236180..7237033, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Deficiency of the mitochondrial ribosomal subunit, MRPL50, causes autosomal recessive syndromic premature ovarian insufficiency.
Title: Deficiency of the mitochondrial ribosomal subunit, MRPL50, causes autosomal recessive syndromic premature ovarian insufficiency.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial translation	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of mitochondrial large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

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