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    CG1764 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32281, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1764provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030467
    Locus tag
    Dmel_CG1764
    See related
    AllianceGenome:FB:FBgn0030467
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg1764; Dmel\CG1764
    Summary
    Predicted to enable amino acid binding activity and dimethylargininase activity. Predicted to be involved in arginine metabolic process; citrulline metabolic process; and positive regulation of nitric oxide biosynthetic process. Is expressed in embryonic Malpighian tubule; embryonic dorsal epidermis; embryonic hindgut; embryonic main segment of Malpighian tubule; and embryonic ventral epidermis. Human ortholog(s) of this gene implicated in cardiovascular system disease; coronary artery disease; and hypertension. Orthologous to human DDAH2 (DDAH family member 2, ADMA-independent) and DDAH1 (dimethylarginine dimethylaminohydrolase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1764 in Genome Data Viewer
    Location:
    11E9-11E9; 1-42 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13294473..13302415, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13188506..13196448, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Remoulade Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45018 Neighboring gene Inositol 1,4,5-triphosphate kinase 2 Neighboring gene Peroxiredoxin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila. Kadener S, et al. Proc Natl Acad Sci U S A, 2006 Sep 5. PMID 16938865, Free PMC Article
    2. The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Anholt RR, et al. Nat Genet, 2003 Oct. PMID 12958599
    3. Genes expressed in the Drosophila head reveal a role for fat cells in sex-specific physiology. Fujii S, et al. EMBO J, 2002 Oct 15. PMID 12374736, Free PMC Article
    4. Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates. Olson JM, et al. G3 (Bethesda), 2019 Nov 5. PMID 31690598, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables amino acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dimethylargininase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in arginine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in citrulline metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of nitric oxide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1764-PA
    CG1764-PB
    NP_001285198.1
    NP_572871.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13294473..13302415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298269.1 → NP_001285198.1  uncharacterized protein Dmel_CG1764, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285198.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYF0
      Conserved Domains (1) summary
      cl19186
      Location:24 → 149
      Amidinotransf; Amidinotransferase

    2. NM_132643.3 → NP_572871.1  uncharacterized protein Dmel_CG1764, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VYF0
      Related
      FBpp0073627
      Conserved Domains (1) summary
      cl19186
      Location:24 → 149
      Amidinotransf; Amidinotransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYF0 Q9VYF0

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