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    CG3358 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35604, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3358provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033117
    Locus tag
    Dmel_CG3358
    See related
    AllianceGenome:FB:FBgn0033117
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3358
    Summary
    Predicted to enable 3'-5'-DNA exonuclease activity. Is expressed in organism. Orthologous to human TATDN1 (TatD DNase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3358 in Genome Data Viewer
    Location:
    42E1-42E1; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6923366..6924929)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2810871..2812434)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Serpin 42De Neighboring gene uncharacterized protein Neighboring gene missing-in-metastasis Neighboring gene transfer RNA:Lysine-CTT 1-6 Neighboring gene Chemosensory protein B 42b Neighboring gene Chemosensory protein B 42c

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin. Golovnin A, et al. PLoS One, 2015. PMID 26489095, Free PMC Article
    2. A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. Lin H, et al. Proc Natl Acad Sci U S A, 2005 Sep 6. PMID 16129837, Free PMC Article
    3. Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila. Hansen KD, et al. PLoS Genet, 2009 Jun. PMID 19543372, Free PMC Article
    4. Active promoters and insulators are marked by the centrosomal protein 190. Bartkuhn M, et al. EMBO J, 2009 Apr 8. PMID 19229299, Free PMC Article
    5. Systems genetics of complex traits in Drosophila melanogaster. Ayroles JF, et al. Nat Genet, 2009 Mar. PMID 19234471, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 3'-5'-DNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3358-PE
    CG3358-PF
    CG3358-PG
    NP_001246156.2
    NP_610248.4
    NP_724515.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6923366..6924929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259227.2 → NP_001246156.2  uncharacterized protein Dmel_CG3358, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246156.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6R8, C9QP59, Q7JUN9
      Conserved Domains (1) summary
      cd01310
      Location:13 → 284
      TatD_DNAse; TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.

    2. NM_136404.4 → NP_610248.4  uncharacterized protein Dmel_CG3358, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610248.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6R8, C9QP59, Q7JUN9
      Conserved Domains (1) summary
      cd01310
      Location:13 → 284
      TatD_DNAse; TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.

    3. NM_165497.3 → NP_724515.1  uncharacterized protein Dmel_CG3358, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724515.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6R8, C9QP59, Q7JUN9
      Related
      FBpp0298012
      Conserved Domains (1) summary
      cd01310
      Location:13 → 284
      TatD_DNAse; TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JUN9 Q7JUN9

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