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    Atac1 Ada2a-containing complex component 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Atac1provided by FlyBase
    Official Full Name
    Ada2a-containing complex component 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0031876
    Locus tag
    Dmel_CG9200
    See related
    AllianceGenome:FB:FBgn0031876
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9200; dAtac1; dATAC1; Dmel\CG9200
    Summary
    Involved in chromatin remodeling. Part of ATAC complex. Orthologous to human ZZZ3 (zinc finger ZZ-type containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Atac1 in Genome Data Viewer
    Location:
    27C7-27C7; 2-23 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (6959099..6960328, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (6959099..6960328, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gas41 Neighboring gene Stromalin 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene 3-Hydroxymethyl-3-methylglutaryl-CoA lyase Neighboring gene septin interacting protein 2 Neighboring gene Coproporphyrinogen oxidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila. Guelman S, et al. Mol Cell Biol, 2006 Feb. PMID 16428443, Free PMC Article
    2. ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Suganuma T, et al. Nat Struct Mol Biol, 2008 Apr. PMID 18327268
    3. A metazoan ATAC acetyltransferase subunit that regulates mitogen-activated protein kinase signaling is related to an ancient molybdopterin synthase component. Suganuma T, et al. Mol Cell Proteomics, 2012 May. PMID 22345504, Free PMC Article
    4. The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Guelman S, et al. Mol Cell Biol, 2006 Oct. PMID 16980620, Free PMC Article
    5. The ATAC acetyltransferase complex coordinates MAP kinases to regulate JNK target genes. Suganuma T, et al. Cell, 2010 Sep 3. PMID 20813260

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ATAC does not show nucleosome-remodeling activity itself, it stimulates nucleosome sliding by the ISWI, SWI-SNF and RSC complexes
      Title: ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding.
    2. a novel SANT domain protein, named Atac1 (ATAC component 1), copurifies with ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex.
      Title: Host cell factor and an uncharacterized SANT domain protein are stable components of ATAC, a novel dAda2A/dGcn5-containing histone acetyltransferase complex in Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATAC complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ada2a-containing complex component 1
    Names
    ATAC component 1
    Atac1-PA
    CG9200-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      6959099..6960328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135244.4 → NP_609088.1  Ada2a-containing complex component 1 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609088.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VM59
      Related
      FBpp0078990
      Conserved Domains (2) summary
      smart00717
      Location:135 → 185
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:135 → 183
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VM59 Q9VM59

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