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    Nup205 Nucleoporin 205kD [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33002, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nup205provided by FlyBase
    Official Full Name
    Nucleoporin 205kDprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031078
    Locus tag
    Dmel_CG11943
    See related
    AllianceGenome:FB:FBgn0031078
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey281; CG11943; Dmel\CG11943; nup205; Ov4
    Summary
    Predicted to be a structural constituent of nuclear pore. Involved in gravitaxis and protein import into nucleus. Predicted to be part of nuclear pore inner ring. Is expressed in several structures, including eye disc posterior to the morphogenetic furrow; gonad; larval central nervous system; organism subdivision; and salivary gland. Human ortholog(s) of this gene implicated in nephrotic syndrome type 13. Orthologous to human NUP205 (nucleoporin 205). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Nup205 in Genome Data Viewer
    Location:
    18F4-18F4; 1-64 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (19852214..19859379)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19746247..19753412)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene SKP1-related E Neighboring gene pico Neighboring gene THADA Neighboring gene Histone gene-specific Epigenetic Repressor in late S phase Neighboring gene amnesiac

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in gravitaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear pore organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear pore organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nuclear pore inner ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nuclear pore inner ring ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    nucleoporin 205kD
    Names
    CG11943-PA
    CG11943-PB
    Nup205-PA
    Nup205-PB
    nucleoporin 205

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      19852214..19859379
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167687.3 → NP_728308.1  nucleoporin 205kD, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728308.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B6IDH1, Q3YMV0, Q8IQV9, Q8MSV6, Q9VWB8
      Related
      FBpp0074567
      Conserved Domains (1) summary
      pfam11894
      Location:32 → 1796
      Nup192; Nuclear pore complex scaffold, nucleoporins 186/192/205

    2. NM_134518.4 → NP_608362.2  nucleoporin 205kD, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608362.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VWB8
      Related
      FBpp0074568
      Conserved Domains (1) summary
      pfam11894
      Location:9 → 1772
      Nup192; Nuclear pore complex scaffold, nucleoporins 186/192/205
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQV9.1 Q8IQV9

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