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    Fcgbpl1 Fc fragment of IgG binding protein-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292746, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fcgbpl1provided by RGD
    Official Full Name
    Fc fragment of IgG binding protein-like 1provided by RGD
    Primary source
    RGD:1311906
    See related
    EnsemblRapid:ENSRNOG00000042899 AllianceGenome:RGD:1311906
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311906
    Summary
    Predicted to be active in extracellular matrix and extracellular space. Orthologous to human FCGBP (Fc gamma binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 3.0), Uterus (RPKM 2.7) and 9 other tissues See more
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    Genomic context

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    See Fcgbpl1 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (92552363..92590377)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (83424788..83462802)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (85058541..85096492)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene Fc gamma binding protein Neighboring gene RNA, U6 small nuclear 105 Neighboring gene fibrillarin Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 1B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Differential gene expression pattern of diabetic rat retinas after intravitreal injection of erythropoietin. Chu Q, et al. Clin Exp Ophthalmol, 2011 Mar. PMID 20973890
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Fc fragment of IgG binding protein-like
    Names
    IgG Fc binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164656.1 → NP_001158128.1  Fc fragment of IgG binding protein-like precursor

      Status: VALIDATED

      Source sequence(s)
      BC099756, CA334702, CB547115, DN933897, DN936606, JAXUCZ010000001
      UniProtKB/TrEMBL
      F7EZQ4
      Related
      ENSRNOP00000053948.3, ENSRNOT00000057120.5
      Conserved Domains (7) summary
      smart00216
      Location:831 → 988
      VWD; von Willebrand factor (vWF) type D domain
      smart00832
      Location:1033 → 1108
      C8; This domain contains 8 conserved cysteine residues
      pfam00094
      Location:56 → 212
      VWD; von Willebrand factor type D domain
      pfam01826
      Location:1916 → 1969
      TIL; Trypsin Inhibitor like cysteine rich domain
      pfam08742
      Location:644 → 714
      C8; C8 domain
      cl02516
      Location:2404 → 2558
      VWD; von Willebrand factor type D domain
      cl17735
      Location:773 → 827
      VWC; von Willebrand factor type C domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      92552363..92590377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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