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    Slc35f6 solute carrier family 35, member F6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298851, updated on 27-Nov-2024

    Summary

    Official Symbol
    Slc35f6provided by RGD
    Official Full Name
    solute carrier family 35, member F6provided by RGD
    Primary source
    RGD:1309228
    See related
    EnsemblRapid:ENSRNOG00000009459 AllianceGenome:RGD:1309228
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ANT2BP; RGD1309228
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and positive regulation of cell population proliferation. Predicted to be located in several cellular components, including lysosomal membrane; mitochondrion; and nucleoplasm. Predicted to be active in intracellular membrane-bounded organelle and membrane. Orthologous to human SLC35F6 (solute carrier family 35 member F6). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 59.6), Brain (RPKM 56.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc35f6 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (31445738..31457580, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (25725822..25737720, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (27095144..27106982, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene centromere protein A Neighboring gene uncharacterized LOC134479331 Neighboring gene uncharacterized LOC134479332 Neighboring gene potassium two pore domain channel subfamily K member 3 Neighboring gene uncharacterized LOC134479333

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 35 member F6
    Names
    ANT2-binding protein
    transmembrane protein C2orf18 homolog
    transport and Golgi organization 9 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017451.1NP_001017451.1  solute carrier family 35 member F6 precursor

      See identical proteins and their annotated locations for NP_001017451.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085904
      UniProtKB/Swiss-Prot
      Q5RKH7
      UniProtKB/TrEMBL
      A0A8I5ZTZ0, A6HAC9
      Related
      ENSRNOP00000012558.5, ENSRNOT00000012558.8
      Conserved Domains (1) summary
      pfam04142
      Location:106158
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      31445738..31457580 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063261632.1XP_063117702.1  solute carrier family 35 member F6 isoform X1

      Related
      ENSRNOP00000082156.2, ENSRNOT00000095130.2