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    nbr1a NBR1 autophagy cargo receptor a [ Danio rerio (zebrafish) ]

    Gene ID: 337168, updated on 4-Jan-2025

    Summary

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    Official Symbol
    nbr1aprovided by ZNC
    Official Full Name
    NBR1 autophagy cargo receptor aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9112
    See related
    Ensembl:ENSDARG00000077297 AllianceGenome:ZFIN:ZDB-GENE-030131-9112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nbr1; fa99f08; wu:fa99f08
    Summary
    Orthologous to human NBR1 (NBR1 autophagy cargo receptor). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See nbr1a in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (27213733..27229860)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (27122372..27138500)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100535964 Neighboring gene homeobox B1b Neighboring gene src kinase associated phosphoprotein 1 Neighboring gene proteasome activator subunit 3 Neighboring gene uncharacterized LOC110440144 Neighboring gene transmembrane protein 106A Neighboring gene ADP-ribosylation factor-like 4D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    NBR1 autophagy cargo receptor a
    Names
    neighbor of brca1 gene 1
    neighbor of brca1 gene 1a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305595.1 → NP_001292524.1  NBR1 autophagy cargo receptor a

      Status: VALIDATED

      Source sequence(s)
      BX001014
      UniProtKB/TrEMBL
      A0A8M1P6X5, A0A8M9QE48, E9QEG9
      Related
      ENSDARP00000121070.1, ENSDART00000133048.3
      Conserved Domains (4) summary
      cd14319
      Location:939 → 977
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      pfam16158
      Location:373 → 472
      N_BRCA1_IG; Ig-like domain from next to BRCA1 gene
      cl00295
      Location:213 → 251
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cl02720
      Location:5 → 83
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      27213733..27229860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001920581.7 → XP_001920616.3  NBR1 autophagy cargo receptor a isoform X1

      UniProtKB/TrEMBL
      A0A8M1QKG5, A0A8M9Q884
      Related
      ENSDART00000138141.2
      Conserved Domains (4) summary
      cd14319
      Location:958 → 996
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      pfam16158
      Location:392 → 491
      N_BRCA1_IG; Ig-like domain from next to BRCA1 gene
      cl00295
      Location:213 → 251
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cl02720
      Location:5 → 83
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394847.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      117849..133976
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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